What is glimepiride and metformin?
Glimepiride + Metformin is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride + Metformin is used to Treat : Control high blood sugar in people with type 2 diabetes. Glimepiride + Metformin may also be used with other diabetes medications.
Is it safe to take metformin and glimepiride together?
Using metFORMIN together with glimepiride can increase the risk of hypoglycemia, or low blood sugar. You may need a dose adjustment or more frequent monitoring of your blood sugar to safely use both medications. Let your doctor know if you experience hypoglycemia during treatment.
Is glimepiride bad for kidneys?
In conclusion glimepiride is safe, effective and has clearly-definable pharmacokinetics in diabetic patients with renal impairment. The increased plasma elimination of glimepiride with decreasing kidney function is explainable on the basis of altered protein binding with an increase in unbound drug.
What are the side effects of metformin and glimepiride?
The more common side effects that can occur with glimepiride include:
- low blood sugar (hypoglycemia). Symptoms may include: trembling or shaking. nervousness or anxiety. irritability. sweating. lightheadedness or dizziness. headache. fast heart rate or palpitations.
- unexplained weight gain.
Is metformin and glimepiride same?
Metformin was only more effective than glimepiride in controlling the levels of total cholesterol (TC, 0.33 [0.03, 0.63], P = 0.03), low-density lipoprotein (LDL, 0.35 [0.16, 0.53], P = 0.0002) and triglycerides (TG, 0.26 [0.05, 0.46], P = 0.01).
Which is stronger glimepiride or metformin?
Which is safer glimepiride or metformin?
A single severe hypoglycemic event occurred in each group. CONCLUSIONS—Glimepiride reduced A1C similarly to metformin with greater weight gain, and there was comparable safety over 24 weeks in the treatment of pediatric subjects with type 2 diabetes.
Why is metformin a combination of glimepiride?
The combination of modern sulfonylurea (glimepiride) and metformin is widely prescribed for effective blood glucose control due to its capability of counteracting “insulin secretion disorder” and “insulin resistance,” respectively.
Can I take glimepiride without metformin?
Glimepiride can be prescribed on its own or together with other diabetes medicines. It’s usually prescribed if you can’t take metformin, or if metformin on its own isn’t keeping your blood sugar under control.
When to take glimepiride?
Glimepiride comes as a tablet to take by mouth. It is usually taken once a day with breakfast or the first main meal of the day. To help you remember to take glimepiride, take it at around the same time every day.
What are the side effects of glimepiride?
Possible serious side effects of glimepiride include: Anemia. Low blood platelets. Low sodium. Sensitivity to sunlight. Liver dysfunction.
Is metformin and Glipizide the same pill?
Glipizide-metformin tablets contain two different medications in the same pill. Glipizide is a type of medication called a sulfonylurea, and it works by decreasing the liver’s production of sugar and increasing the release of insulin from pancreas. Metformin is a type of medication called a biguanide,…
Is glimepiride a controlled drug?
Glimepiride is used in the treatment of diabetes, type 2 and belongs to the drug class sulfonylureas. Risk cannot be ruled out during pregnancy. Glimepiride 2 mg is not a controlled substance under the Controlled Substances Act (CSA).