What are the differential diagnosis of bullous pemphigoid?
As BP may have a polymorphic presentation with non-bullous manifestations and blisters, a wide range of differential diagnosis should be considered: pemphigus foliaceus, pemphigus herpetiformis, linear IgA bullous dermatosis, epidermolysis bullosa acquisita, bullous lupus erythematosus, eczema, urticaria, prurigo.
What infections cause bullae?
Viruses. Infection by certain viruses can result in bullae appearing on your skin. For example, many people who have shingles, which is caused by a virus, will experience bullae as a symptom. These will often appear as a single stripe of fluid-filled blisters that break easily.
What is the difference between bullous pemphigus and bullous pemphigoid?
Pemphigus affects the outer of the skin (epidermis) and causes lesions and blisters that are easily ruptured. Pemphigoid affects a lower layer of the skin, between the epidermis and the dermis, creating tense blisters that do not break easily.
What is bullous infection?
Infectious disease/dermatology. Bullous impetigo is a bacterial skin infection caused by Staphylococcus aureus that results in the formation of large blisters called bullae, usually in areas with skin folds like the armpit, groin, between the fingers or toes, beneath the breast, and between the buttocks.
What is bullous lung disease?
Bullous lung disease is characterized by the development of bullae within the lung parenchyma. A bulla is a permanent, air-filled space within the lung parenchyma that is at least 1 cm in size and has a thin or poorly defined wall; it is bordered only by remnants of alveolar septae and/or pleura.
What are the differential diagnoses of bullous disease?
Author: Sofia Junaid Syed, MD, MPH; Chief Editor: Dirk M Elston, MD more… The differential diagnosis includes friction bullae, bullae due to burns or edema, bullous fixed drug reaction, bullous pemphigoid, and epidermolysis bullosa acquisita.
What kind of disease is bullous lichen planus?
Bullous lichen planus is a rare variant of lichen planus. It is characterized by vesicles or bullae, which usually develop in the context of pre-existing LP lesions. It is often misdiagnosed and should be differentiated from other subepidermal bullous diseases especially lichen planus pemphigoides.
Are there any autoimmune bullous dermatoses that are serious?
Some bullous diseases have serious sequelae, necessitating early treatment and intervention to prevent further morbidity or mortality. Auto-immune blistering diseases include pemphigus vulgaris, paraneoplastic pemphigus, bullous pemphigoid, cicatricial pemphigoid, dermatitis herpetiformis, and linear IgA dermatosis ( Table 2). TABLE 2.
What are the symptoms of bullous pemphigoid ( BP )?
General Discussion. Bullous pemphigoid (BP) is a rare, autoimmune, chronic skin disorder characterized by blistering, urticarial lesions (hives) and itching. Less commonly these blisters can involve the mucous membranes including the eyes, oral mucosa, esophagus and genital mucosa.