Tips

Is it safe for a pregnant woman to take ondansetron?

Is it safe for a pregnant woman to take ondansetron?

Zofran is approved by the Food and Drug Administration (FDA) for use to fight off nausea related to chemotherapy. It is not currently approved by the FDA for morning sickness. Even so, most studies show that ondansetron is safe to use during the first trimester when most women experience morning sickness.

Does ondansetron cause miscarriage?

There are no concerns that ondansetron use in pregnancy affects the chance of miscarriage, stillbirth, preterm delivery or low infant birth weight.

How much ondansetron is safe during pregnancy?

Typical dosage for pregnancy nausea The dose of Zofran for hyperemesis gravidarum requiring hospitalization is a maximum of 10 milligrams via intravenous therapy (IV) every 8 hours. More typical pregnancy nausea is managed by a much lower oral dose — 4 to 8 mg every 8 hours.

How do I take ondansetron while pregnant?

Ondansetron has also been prescribed during pregnancy to help with symptoms of nausea and vomiting in pregnancy (NVP). NVP is also referred to as “morning sickness”. Ondansetron is taken by mouth, infused into a vein (by IV) or given by injection into a muscle (IM).

Can ondansetron cause birth defects?

The results of these studies have concluded Zofran causes birth defects, particularly congenital heart defects, cleft palate defects, and kidney defects. The birth defects linked to use of Zofran during pregnancy include: 130% risk of overall birth defects.

What nausea medicine is safe while pregnant?

In fact, the FDA has approved a prescription medication for use during pregnancy that is a combination of Vitamin B6 and Unisom. It is called Diclegis. This is the only FDA approved medication for treating nausea and vomiting during pregnancy.

What is the best anti-nausea medication for pregnancy?

Is it safe to take ondansetron during pregnancy?

The safety of ondansetron during pregnancy has-following publication of controversial and seemingly contradictory results-been subject to considerable academic turmoil, specifically with respect to the risk of congenital cardiac malformations and oral cleft.

When to use ondansetron for nausea and vomiting?

Ondansetron is an effective antiemetic that is being widely used as a second-line treatment option for severe nausea and vomiting of pregnancy in accordance with clinical guidelines.

Is there a link between ondansetron and congenital malformations?

While further investigation of the literature is needed, our results highlight the paucity of evidence linking prenatal exposure to ondansetron to an increased risk of congenital malformations. There is a need for additional epidemiologic studies to confirm whether ondansetron represents a safe and …

Is it safe to use ondansetron for NVP?

AnswerDuring the past decade ondansetron has been increasingly used in the United States for NVP, owing to the lack of an FDA-approved drug for this condition. While fetal safety data for doxylamine-pyridoxine are based on more than a quarter of a million pregnancies, the fetal safety data for ondansetron are based on fewer than 200 births.

Share this post