What is meant by a pyknotic nucleus?
Pyknosis, or karyopyknosis, is the irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis or apoptosis. The maturing neutrophil will condense its nucleus into several connected lobes that stay in the cell until the end of its cell life.
What causes Pyknotic nucleus?
Pyknosis occurs in senescent (old) leukocytes and results from preprogrammed cell death (apoptosis). With pyknosis, the nucleus becomes dense and compact and begins to fragment (karyorrhexis) resulting in spheres of dark-staining nuclear chromatin.
What is the meaning of Karyolysis?
Medical Definition of karyolysis : dissolution of the cell nucleus with loss of its affinity for basic stains sometimes occurring normally but usually in necrosis — compare karyorrhexis.
What is Karyolysis and Pyknosis?
Pyknosis is the process of nuclear shrinkage. It is an irreversible condition of chromatin in the nucleus of a cell wall undergoing necrosis or apoptosis. Karyolysis is a complete dissolution of the chromatin of a dying cell due to enzymatic degradation by endonucleases.
What does Pyknotic mean?
Medical Definition of pyknosis : a degenerative condition of a cell nucleus marked by clumping of the chromosomes, hyperchromatism, and shrinking of the nucleus.
What is Liquefactive?
Liquefactive necrosis (or colliquative necrosis) is a type of necrosis which results in a transformation of the tissue into a liquid viscous mass. Often it is associated with focal bacterial or fungal infections, and can also manifest as one of the symptoms of an internal chemical burn.
What causes Necroptosis?
Necroptosis is a programmed form of necrosis, or inflammatory cell death. Conventionally, necrosis is associated with unprogrammed cell death resulting from cellular damage or infiltration by pathogens, in contrast to orderly, programmed cell death via apoptosis.
What is Pyknotic?
: a degenerative condition of a cell nucleus marked by clumping of the chromosomes, hyperchromatism, and shrinking of the nucleus.
What is Parachromatin?
: any of various nonstaining or feebly straining nuclear elements that are a particular kind of protoplasm (as linin or spindle fibers) or are various artifacts.
Which is a characteristic feature of a pyknotic nucleus?
Some of their nuclei were pyknotic: a crescent-shaped chromatin and cytoplasm material was distinguished as being of a characteristic feature of apoptosis (Fig. Atresia and Apoptosis in Pre- and Postovulatory Follicles of Sharptooth Catfish (Clarias gariepinus, Burchell, 1822)
Where are pyknotic nuclei found in a neutrophil?
The maturing neutrophil will condense its nucleus into several connected lobes that stay in the cell until the end of its cell life. Micrograph of an infarct in the biliary tract, with pyknotic nuclei (arrows) (400x). Pyknotic nuclei are often found in the zona reticularis of the adrenal gland.
What does a pyknotic cell on a blood smear mean?
Therefore, pyknotic cells have an intact cytoplasmic membrane with one or more, variably sized, dense, round, dark nuclear fragments. The presence of pyknotic cells generally indicates a delay (hours) in making the blood smear after blood collection.
What are the morphological characteristics of pyknosis?
Morphological characteristics of pyknosis and other forms of nuclear destruction Pyknosis, or karyopyknosis, is the irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis or apoptosis. It is followed by karyorrhexis, or fragmentation of the nucleus.