Is Cresemba generic?
No. There is currently no therapeutically equivalent version of Cresemba available in the United States. Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Cresemba. These medications may be counterfeit and potentially unsafe.
What is Cresemba used for?
This medication is used to treat certain serious fungal infections. This medication is known as an azole antifungal. It works by stopping the growth of fungi.
How do you administer Cresemba injection?
Intravenous formulation must be administered via an infusion set with an in-line filter (pore size 0.2 to 1.2 micron). Infuse the intravenous formulation over a minimum of 1 hour in 250 mL of a compatible diluent, to reduce the risk for infusion-related reactions. Do not administer as an intravenous bolus injection.
When is isavuconazole used?
The recommended dose for both oral and IV administration is a loading dose of 200 mg of isavuconazole (equivalent to 372 mg of isavuconazonium sulfate) every 8 hours for six doses given over a 48-hour period, followed by a maintenance dose of 200 mg of isavuconazole daily.
How much does CRESEMBA cost?
The cost for Cresemba intravenous powder for injection 372 mg is around $349 for a supply of 1 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans….Intravenous Powder For Injection.
Is CRESEMBA an antibiotic?
Cresemba (isavuconazonium) is an antifungal medication that fights infections caused by fungus. Cresemba is a prescription medicine used to treat infections caused by certain types of fungus (aspergillosis or mucormycosis) in patients 18 years of age and older.
Is Cresemba an antibiotic?
How much does Cresemba cost?
How long does Cresemba stay in system?
Isavuconazole has an oral bioavailability of 98%, an intravenous (IV) volume of distribution of 450 L, a plasma half-life of 130 hours, and is 99% protein-bound.
What is the solubility of Isavuconazonium sulfate?
Isavuconazonium sulfate is an amorphous material. Its solubility is >1.0 g/ml in any of the pH conditions tested (pH 1, 3, 5 and 7) and it is a BCS class I substance.
What kind of prodrug is Isavuconazole sulfate used for?
Isavuconazonium sulfate (BAL8557; trade name Cresemba) is a prodrug for isavuconazole which is a triazole antifungal agent. Isavuconazonium is used to treat invasive aspergillosis and invasive mucormycosis.
How often do you take Isavuconazonium sulfate capsules?
Loading Dose: 372 mg isavuconazonium sulfate (equivalent to 200 mg of isavuconazole) every 8 hours for 6 doses (48 hours) via oral (2 capsules) or intravenous administration (1 reconstituted vial) ( 2.2).
How much Isavuconazonium sulfate is in CRESEMBA capsules?
CRESEMBA capsules contain 186 mg of isavuconazonium sulfate (equivalent to 100 mg of isavuconazole). ( 3) CRESEMBA for injection is supplied in a single-dose vial as a sterile lyophilized powder containing 372 mg of isavuconazonium sulfate (equivalent to 200 mg of isavuconazole). ( 3) Hypersensitivity to CRESEMBA. ( 4)